Uremia by ureteral obstruction is one of the causes of deathes in gynecologic malignancies. So if the clinicians will manage the urteral obstruction successfully, many patients can obtained longer survival with further aggressive treatment,
chemotherapy
or radiotherapy. Percutaneous neophrostomy (PCN) is one of good modalities to manage that problems. From January, 1986 to December, 1992, PCNs were performed in 103 patients with ureteral obstruction caused by gynecologic malignancies in Korea
Cancer
Center Hospital.
Etiology of ureteral obstruction was classified with untreated advanced cancer (N:23),recurrent cancer (N: 54), persistant cancer (N: 19), post-radiotherapy (N: 3), post-operation (N: 2), and others (N:2). The improvement of renal function after
PCN was
found in 92.2%(95/103) of patients and the recovery rate of serum creatinine to below 1.5mg/dl after PCN was 56.8%(50/88). Forty eight patients(50.0%)could be given adjuvant therapy aginst cancer after PCN and especially more frequently in
advanced
cancer. The removal of PCN catheter in 7 patients (6.8%) could be made successfully and the drainage time averaged 3.2 months.
These data suggests that PCN was a simple effective and safe procedure for obstructuve uremic patients with advanced gynecologic cancers. PCN can be used to improve renal function and to allow palliative therazy.
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